Whenever a residence is to be constructed upon a corner lot, upon a lot of extraordinary or unusual size and shape or upon a lot which, because of the terrain and grade of the land, is difficult or impossible to determine the proper application of the provisions of this Chapter thereto, then the Zoning Commission shall in all such cases have the power and authority to designate the proper location of such structure upon any such lot, including the manner in which it shall front and the front, side and rear yard depth requirements, in order that any such structure will comply in all respects with the intent and purposes of this Chapter as it is applicable to the immediate vicinity.