A single-family dwelling may be constructed on any recorded lot held in single and separate ownership prior to adoption of these regulations without regard to the minimum lot area, minimum lot width, and minimum lake or river frontage required by this chapter, provided that such lot does not adjoin any other lot or lots held by the same owner such that the owner might combine two or more lots in order to meet minimum requirements. Minimum front, side and rear building setback requirements, and maximum building coverage and minimum open space requirements stated in this chapter shall apply, and any deviation from such requirements shall require a variance. The establishment of a use other than a single-family dwelling on such lots shall require a variance.