Whenever the owners of 50% or more of an area in any district or a specified portion thereof shall present a signed petition to the Village Board requesting any amendment, supplement, alterations, change in or repeal of the regulations for such district or specified portion thereof, it shall be the duty of the Board of Trustees to hold a public hearing or hearings thereon and give such notice thereof as required by statute; and if the Board deems it advisable, it may, in addition to such statutory notice, cause written notice to be served, either by mail or personally, upon the owners of all lands within the district or specified portion thereof which such proposed amendment, supplement, alteration, change in or a repeal shall relate to and, in addition thereto, upon the owners of all lands lying within a distance of 100 feet of such district or specified portion thereof. A sufficient notice shall be a written notice mailed or personally served upon the owners of lands so affected whose names shall appear upon the last completed Village assessment roll. It shall be the duty of the Board after public notice and hearings to decide by majority vote upon such petition within 90 days after the filing of such petition with the Clerk of the Village; provided, however, that in the case of a protest against such change signed by the owners of 20% or more either of the area of lots included in such proposed change or of those immediately adjacent in the rear thereof extending 100 feet therefrom or of those directly opposite thereto extending 100 feet from the street frontage of such opposite lots, such amendment shall not become effective except by a favorable vote of all the members of the Board of Trustees.