When required. No building or structure shall be erected, added to, placed upon property, or structurally altered until a permit therefore has been issued by the Zoning Officer. Construction and/or alteration as authorized by an approved permit shall begin within the period of 180 days of the date of issuance, otherwise, the permit is null and void. If zoning requirements change a maximum of one ninety-day extension may be granted. All applications for zoning permits shall be in accordance with the requirements of this chapter, and unless a variance is granted by the Zoning Hearing Board, no such permit shall be issued for any building where said construction, addition or alteration for use thereof would be in violation of any of the provisions of this chapter.